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Retatrutide / Reta (lyophilized).
Retatrutide is an investigational triple-hormone receptor agonist designed to target metabolic pathways involved in weight management and glucose regulation. By engaging GLP-1, GIP, and glucagon receptors, it is being studied for its potential role in supporting metabolic health and body composition outcomes.
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Certificate of Analysis
Third-party tested for 99% purity, ID, quantity.
Certificate of Analysis
Third-party tested for 99% endotoxin.
Research use only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Retatrutide has been investigated primarily in metabolic and endocrine research contexts as a tool for studying simultaneous agonism across three energy-regulating receptors. Reported research characterizes nanomolar-range potency at GCGR, GIPR, and GLP-1R and dose-dependent changes in body weight and hepatic-fat measures across preclinical and Phase 2 study windows.
Key Areas of Research:
– Metabolic / Body Composition: body weight, adiposity, abdominal-fat distribution
– Endocrine / Incretin Signaling: combined GIP, GLP-1 and glucagon receptor activation; insulin sensitivity and glucose handling
– Hepatic / Lipid Metabolism: hepatic fat content and lipid-metabolism markers
– Systemic / Cardiometabolic: dose-related physiological responses
– Body-weight and adiposity regulation research models
– Mechanistic tool for simultaneous tri-receptor (GIP/GLP-1/glucagon) agonism
– Hepatic fat content and lipid-metabolism endpoints
– Glycemic control and insulin-signaling pathway research
CAS #: 2381089-83-2
Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight: 4845.44 g/mol
PubChem ID: 474492335
NEJM 2023 (Jastreboff et al.): https://doi.org/10.1056/NEJMoa2301972
Nature Medicine 2024 (Sanyal et al.): https://doi.org/10.1038/s41591-024-03018-2
PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/485663353
Store sealed vials refrigerated at 2–8°C, away from light; refrigerate after reconstitution and avoid freeze-thaw cycles. For research use only, handle with proper PPE in a controlled lab setting.
A team representative will call to confirm your order before it’s dispatched. Once confirmed, orders ship within 24 hours in discreet, temperature-conscious packaging, with tracking provided.
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Carefully freeze-dried for stability, consistency, and reliable handling.
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Carefully freeze-dried for stability, consistency, and reliable handling.
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Carefully freeze-dried for stability, consistency, and reliable handling.
Everything you need to know about our products and processes.
What are research peptides? Peptides are short chains of amino acids — the body’s natural signaling molecules involved in repair, metabolism, and hormone regulation. Ours are premium-grade and supplied strictly for laboratory and research use.
What does "research use only" mean? Our products are supplied strictly for laboratory and research purposes — not for human or animal consumption — and are intended to be handled by qualified researchers. Customers are responsible for compliance with their local regulations.
Is Reset Labs legit, and are your peptides tested? Yes. We’re a US-based research peptide lab. Every product is manufactured in the USA and independently batch-tested by Horizon Analytics (HPLC/MS), shipping with a Certificate of Analysis (COA) and full documentation on every order.
Where do you ship, and how fast? We ship worldwide from our US warehouse, and within Colombia from our Colombia warehouse. Orders process within 24 hours, ship in 24–48 hours, and typically deliver in 2–5 business days with tracking. Free shipping on orders over USD $350.
Do you offer discounts? Yes — buy 3 vials of the same compound for 15% off, and first-time customers get an extra 10% off. New customers can stack both.
Do I need a prescription, and how are peptides shipped? No prescription — these are research-use-only materials, not prescription drugs. All products arrive as lyophilized (freeze-dried) powder and require reconstitution with bacteriostatic water before research use.
